RECHERCHE :   Cancers hématologiques
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ETUDE PHASE SITE
AMGEN 20150136: An Observational Study of Blinatumomab Safety and Effectiveness, Utilisation, and Treatment Practices
Leucémie lymphoblastique aigüe (Acute Lymphoblastic leukaemia)
registre
CHUV, HUG
BAY18594 : An open-label, first-in-human, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose and/or recommended Phase II dose of the ATR inhibitor BAY 1895344 in patients with advanced solid tumors and lymphomas
Solid tumors and lymphomas
I
HUG
GRAALL 2014: Multicenter trial for the treatment of Acute Lymphoblastic Leukemia (ALL) in younger adults (18-59 years)
Leucémie lymphoblastique aiguë
III
CHUV, HUG
MATRix / IELSG43: High-dose chemotherapy and autologous stem cell transplant or consolidating conventional chemotherapy in primary CNS lymphoma – randomized phase III trial
Lymphome primitif du système nerveux central (LPSNC / PCNSL)
III
CHUV
SAKK 35/14: Rituximab with or without Ibrutinib for untreated patients with advanced follicular lymphoma in need of therapy. A randomized, double-blinded, SAKK and NLG collaborative Phase II trial
Lymphome folliculaire avancé
II
HUG
SAKK 36/13: Combination of ibrutinib and bortezomib followed by ibrutinib maintenance to treat patients with relapsed and refractory mantle cell lymphoma; a multicenter Phase I/II trial
Lymphome du manteau réfractaire/récidivant
I, II
CHUV, HUG
SAKK 66/18 : Copanlisib in combination with venetoclax in patients with relapsed or refractory B-cell non-Hodgkin lymphoma. A multicenter phase Ib trial with two expansion cohorts
Relapsed or refractory B-cell non-Hodgkin lymphoma
I
HUG
TRIANGLE: autologous Transplantation after a Rituximab/Ibrutinib/Ara-c containing iNduction in Generalized mantle cell Lymphoma – a randomized European MCL Network tria
Lymphome du manteau non traité
III
CHUV, HUG