RECHERCHE :   Cancers hématologiques
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ETUDE PHASE SITE
AMGEN 20150136: An Observational Study of Blinatumomab Safety and Effectiveness, Utilisation, and Treatment Practices
Leucémie lymphoblastique aigüe (Acute Lymphoblastic leukaemia)
registre
CHUV, HUG
BAY18594 : An open-label, first-in-human, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose and/or recommended Phase II dose of the ATR inhibitor BAY 1895344 in patients with advanced solid tumors and lymphomas
Solid tumors and lymphomas
I
HUG
GRAALL 2014: Multicenter trial for the treatment of Acute Lymphoblastic Leukemia (ALL) in younger adults (18-59 years)
Leucémie lymphoblastique aiguë
III
CHUV, HUG
HOVON 150: A phase 3, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib or enasidenib in combination with induction therapy and consolidation therapy followed by maintenance therapy in patients with newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with excess blasts-2, with an IDH1 or IDH2 mutation, respectively, eligible for intensive chemotherapy.
Newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with excess blasts-2, with an IDH1 or IDH2 mutation, respectively, eligible for intensive chemotherapy
III
HUG
MALIBU:Phase II study of combination ibrutinib and rituximab in untreated marginal zone lymphomas
untreated marginal zone lymphomas
II
HUG
SAKK 36/13: Combination of ibrutinib and bortezomib followed by ibrutinib maintenance to treat patients with relapsed and refractory mantle cell lymphoma; a multicenter Phase I/II trial
Lymphome du manteau réfractaire/récidivant
I, II
CHUV, HUG
SAKK 66/18 : Copanlisib in combination with venetoclax in patients with relapsed or refractory B-cell non-Hodgkin lymphoma. A multicenter phase Ib trial with two expansion cohorts
Relapsed or refractory B-cell non-Hodgkin lymphoma
I
HUG
TRIANGLE: autologous Transplantation after a Rituximab/Ibrutinib/Ara-c containing iNduction in Generalized mantle cell Lymphoma – a randomized European MCL Network tria
Lymphome du manteau non traité
III
CHUV, HUG